Unity - how to write unit tests that test game objects

I am a beginner using Unity, I managed to write simple unit tests using the Unity test tools, but now I need to test a bit more complex(not really) classes. Each of these classes has a Game Object which I want to test for certain behavior. How can I achieve this using the Unity test tools? I have tried various different ways, but nothing works. To help a bit illustrate my problem, heres an example class that i would like to test:

using UnityEngine; 
using System.Collections; 

public class Disappear : MonoBehaviour, DisappearInterface 
{ 
    public void Vanish (Collision2D col) 
    { 
       if(col.gameObject.tag == "Player") 
       { 
           Remove(); 
       } 
     } 

     public void Remove () 
     { 
         GameObject.Destroy(this.gameObject, 0.5f); 
     } 

     void OnCollisionEnter2D (Collision2D col) 
     { 
         Vanish(col); 
     } 
}